Identification of Amino Acids within Nonstructural Proteins 10 and 14 of the Avian Coronavirus Infectious Bronchitis Virus That Result in Attenuation <i>In Vivo</i> and <i>In Ovo</i>
Sarah Keep, Phoebe Stevenson-Leggett, Giulia Dowgier, Holly Everest, Graham Freimanis, Michael S. Oade, John A. Hammond, María Armesto, R. Vila, Tura Bru, H.J. Geerligs, Paul Britton, Erica Bickerton
Abstract
The Gammacoronavirus infectious bronchitis virus (IBV) is the etiological agent of infectious bronchitis, an acute, highly contagious, economically important disease of poultry. Vaccination is achieved using a mixture of live attenuated vaccines for young chicks and inactivated vaccines as boosters for laying hens.
Topics & Concepts
BiologyAvian infectious bronchitis virusIn ovoCoronavirusVirologyNidoviralesInfectious bronchitis virusAvian infectious bronchitisCoronaviridaeIn vivoVirusCoronavirus disease 2019 (COVID-19)Infectious disease (medical specialty)GeneticsEmbryoPathologyDiseaseMedicineAnimal Virus Infections StudiesViral gastroenteritis research and epidemiologySARS-CoV-2 and COVID-19 Research