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An in vivo neuroimmune organoid model to study human microglia phenotypes

Simon T. Schafer, Abed AlFatah Mansour, Johannes C. M. Schlachetzki, Monique Pena, Saeed S. Ghassemzadeh, Lisa E. Mitchell, Amanda Mar, Daphne Quang, Sarah Stumpf, Irene Santisteban Ortiz, Addison J. Lana, Clara Baek, Raghad Zaghal, Christopher K. Glass, Axel Nimmerjahn, Fred H. Gage

2023Cell233 citationsDOIOpen Access PDF

Topics & Concepts

MicrogliaBiologyOrganoidNeuroscienceHuman brainIn vivoPhenotypeTranscriptomeXenotransplantationImmunologyInflammationMedicineTransplantationGene expressionGeneGeneticsSurgeryNeuroinflammation and Neurodegeneration MechanismsImmune cells in cancerSingle-cell and spatial transcriptomics
An in vivo neuroimmune organoid model to study human microglia phenotypes | Litcius