An in vivo neuroimmune organoid model to study human microglia phenotypes
Simon T. Schafer, Abed AlFatah Mansour, Johannes C. M. Schlachetzki, Monique Pena, Saeed S. Ghassemzadeh, Lisa E. Mitchell, Amanda Mar, Daphne Quang, Sarah Stumpf, Irene Santisteban Ortiz, Addison J. Lana, Clara Baek, Raghad Zaghal, Christopher K. Glass, Axel Nimmerjahn, Fred H. Gage
Topics & Concepts
MicrogliaBiologyOrganoidNeuroscienceHuman brainIn vivoPhenotypeTranscriptomeXenotransplantationImmunologyInflammationMedicineTransplantationGene expressionGeneGeneticsSurgeryNeuroinflammation and Neurodegeneration MechanismsImmune cells in cancerSingle-cell and spatial transcriptomics