A review of the AJCC melanoma staging system in the TNM classification (eighth edition)
Dai Ogata, Kenjiro Namikawa, Akira Takahashi, Naoya Yamazaki
Abstract
In the eighth edition of the American Joint Committee on Cancer Staging Manual, several modifications were made for melanoma. These modifications were aimed at improving the prognosis prediction accuracy of the staging system. The main modifications are as follows: the cutoff value of the T1 category has been changed, and there are new classifications of stage IIID and of M1d (metastasis of the central nervous system). These changes will allow for more accurate stratification of melanoma prognosis. However, it is necessary to validate the new modifications through future clinical research.
Topics & Concepts
MedicineMelanomaStaging systemStage (stratigraphy)Risk stratificationCutoffCancer stagingMedical physicsOncologyRadiologyCancerInternal medicineCancer researchBiologyPhysicsQuantum mechanicsPaleontologyCutaneous Melanoma Detection and ManagementMelanoma and MAPK PathwaysCAR-T cell therapy research