Monitoring α-synuclein Aggregation Induced by Preformed α-synuclein Fibrils in an <i>In Vitro</i> Model System
Beom Jin Kim, Hye Rin Noh, Hyongjun Jeon, Sang Myun Park
Abstract
model system can be used for high-throughput screening to discover new targets for inhibiting α-syn propagation.
Topics & Concepts
In vitroFibrilGreen fluorescent proteinChemistryProtein aggregationCell biologyBiophysicsNeuroscienceBiologyBiochemistryGeneParkinson's Disease Mechanisms and TreatmentsNeurological disorders and treatmentsBotulinum Toxin and Related Neurological Disorders