Design and synthesis of selective degraders of EGFRL858R/T790M mutant
Xin Zhang, Fang Xu, Linjiang Tong, Tao Zhang, Hua Xie, Xiaoyun Lu, Xiaomei Ren, Ke Ding
Topics & Concepts
ChemistryThreonineMutantProteolysisBiochemistryMethionineT790MProteasomeUbiquitinArginineMutationAmino acidSerineEnzymeGeneKRASProtein Degradation and InhibitorsPeptidase Inhibition and AnalysisMultiple Myeloma Research and Treatments