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Spatial maps of T cell receptors and transcriptomes reveal distinct immune niches and interactions in the adaptive immune response

Sophia Liu, J. Bryan Iorgulescu, Shuqiang Li, Mehdi Borji, Irving Barrera, Vignesh Shanmugam, Haoxiang Lyu, Julia W. Morriss, Zoe N. Garcia, Evan Murray, David A. Reardon, Charles H. Yoon, David A. Braun, Kenneth J. Livak, Catherine J. Wu, Fei Chen

2022Immunity139 citationsDOIOpen Access PDF

Topics & Concepts

BiologyT-cell receptorImmune systemTranscriptomeT cellAcquired immune systemImmune receptorCell biologyImmunologyGeneGene expressionGeneticsSingle-cell and spatial transcriptomicsT-cell and B-cell ImmunologyCAR-T cell therapy research
Spatial maps of T cell receptors and transcriptomes reveal distinct immune niches and interactions in the adaptive immune response | Litcius