Relieving thrombo-inflammation with acid-triggered polymersomes toward ischemic stroke therapy
Ran Li, Zhenhua Wang, Li Jin, Haolong Chen, Xing Guo, Shaobing Zhou
Topics & Concepts
PolymersomeNeutrophil extracellular trapsInflammationThrombusPlateletHyaluronic acidTLR4Ischemic strokeIschemiaDownregulation and upregulationCell biologyChemistryPharmacologyMedicineImmunologyCardiologyBiologyBiochemistryAmphiphileGeneAnatomyCopolymerOrganic chemistryPolymerNeutrophil, Myeloperoxidase and Oxidative MechanismsS100 Proteins and AnnexinsNeuroinflammation and Neurodegeneration Mechanisms