Neonatal Multisystem Inflammatory Syndrome secondary to SARS‐CoV‐2 infection
Shivashankar Diggikar, Ranjith Nanjegowda, Ajay Kumar, Vimal Kumar, Srikant Kulkarni, Praveen Venkatagiri
Abstract
SARS-CoV-2 infection in children accounts for about 1-8% of cases world-wide, most of them asymptomatic or mildly symptomatic. Neonatal infection is rare and usually asymptomatic. Since April 2020, severe manifestations were seen in children in Europe and North America, presenting as Kawasaki disease-like illness involving multiple organs. The Centers for Disease Control and Prevention termed this multisystem inflammatory syndrome in children (MIS-C) and developed a case definition. The World Health Organization developed a similar case definition with slight modifications. The appropriateness of this definition for neonatal scenarios is debatable. Anecdotal reports reveal that the second wave of SARS-CoV-2 in the Indian context has affected neonates with more severity and a wide spectrum of presentations. ]