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Estimating the infection and case fatality ratio for coronavirus disease (COVID-19) using age-adjusted data from the outbreak on the Diamond Princess cruise ship, February 2020

Timothy Russell, Joel Hellewell, Christopher I Jarvis, Kevin van Zandvoort, Sam Abbott, Ruwan Ratnayake, CMMID COVID-19 working group, Stefan Flasche, Rosalind M. Eggo, W. John Edmunds, Adam J. Kucharski

2020Eurosurveillance487 citationsDOIOpen Access PDF

Abstract

Adjusting for delay from confirmation to death, we estimated case and infection fatality ratios (CFR, IFR) for coronavirus disease (COVID-19) on the Diamond Princess ship as 2.6% (95% confidence interval (CI): 0.89-6.7) and 1.3% (95% CI: 0.38-3.6), respectively. Comparing deaths on board with expected deaths based on naive CFR estimates from China, we estimated CFR and IFR in China to be 1.2% (95% CI: 0.3-2.7) and 0.6% (95% CI: 0.2-1.3), respectively.

Topics & Concepts

Coronavirus disease 2019 (COVID-19)Confidence intervalOutbreakMedicineCase fatality rateSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakCoronavirusInternal medicineVirologyDemographyEpidemiologyDiseaseInfectious disease (medical specialty)SociologyCOVID-19 epidemiological studiesInfluenza Virus Research StudiesCOVID-19 Pandemic Impacts