Discovery of spirooxindole–ferrocene hybrids as novel MDM2 inhibitors
Jun Mu, Xin Xie, Shanshan Xiong, Yuehua Zhang, Yuting Wang, Qian Zhao, Hongping Zhu, Wei Huang, Gu He
Topics & Concepts
ChemistryFerroceneMdm2Combinatorial chemistryIn vitroDocking (animal)Small moleculeApoptosisBiochemistryStereochemistryComputational biologyBiologyElectrochemistryMedicineNursingElectrodePhysical chemistryFerrocene Chemistry and ApplicationsSynthesis and Biological EvaluationChemical Synthesis and Analysis