Ligand-based 3D pharmacophore modeling, virtual screening, and molecular dynamic simulation of potential smoothened inhibitors
Alireza Mohebbi
Topics & Concepts
PharmacophoreSmoothenedVirtual screeningChemistryDocking (animal)Ligand (biochemistry)Molecular dynamicsHedgehogComputational biologyBiochemistryStereochemistryBiologySignal transductionReceptorMedicineComputational chemistryNursingHedgehog Signaling Pathway StudiesCancer-related Molecular PathwaysNeurological diseases and metabolism