Cryo-EM and MD infer water-mediated proton transport and autoinhibition mechanisms of V <sub>o</sub> complex
Soung‐Hun Roh, Mrinal Shekhar, Grigore Pintilie, Christophe Chipot, Stephan Wilkens, Abhishek Singharoy, Wah Chiu
Abstract
A 2.7-Å cryo-EM structure and MD simulations explain water-mediated H + transport and autoinhibition of yeast V o proton channel.
Topics & Concepts
ProtonBiophysicsComputational biologyChemistryComputer sciencePhysicsBiologyNuclear physicsATP Synthase and ATPases ResearchPhotosynthetic Processes and MechanismsElectron Spin Resonance Studies