SLIT2 promoter hypermethylation-mediated SLIT2-IT1/miR-218 repression drives leukemogenesis and predicts adverse prognosis in myelodysplastic neoplasm
Ting‐juan Zhang, Zi‐jun Xu, Xiang‐mei Wen, Yu Gu, Ji‐chun Ma, Qian Yuan, Jiang Lin, Jing-dong Zhou, Jun Qian
Topics & Concepts
Cancer researchDNA methylationEpigeneticsMethylationBiologyMyeloid leukemiaCpG sitePromotermicroRNAMyelodysplastic syndromesGeneGene expressionImmunologyGeneticsBone marrowCancer-related molecular mechanisms researchAcute Myeloid Leukemia ResearchEpigenetics and DNA Methylation