Probing the Molecular Assembly of a Metabolizer Drug with β-Cyclodextrin and Its Binding with CT-DNA in Augmenting Antibacterial Activity and Photostability by Physicochemical and Computational Methodologies
Modhusudan Mondal, Shatarupa Basak, Debadrita Roy, Md Salman Haydar, Subhankar Choudhury, Biswajit Ghosh, Narendra Nath Ghosh, Ankita Dutta, Palash Mandal, Kanak Roy, Anoop Kumar, Mahendra Nath Roy
Abstract
) in comparison to Gram-positive bacteria. The encapsulation mode of the dyphylline molecule into the cavity of the β-CD was also investigated using DFT to confirm preliminary results.
Topics & Concepts
CyclodextrinChemistryStoichiometryEscherichia coliAntibacterial activityAqueous solutionCombinatorial chemistryMoleculeDNABeta-CyclodextrinsNuclear chemistryChromatographyOrganic chemistryBacteriaBiochemistryBiologyGeneGeneticsDrug Solubulity and Delivery SystemsAnalytical Chemistry and ChromatographyMicrofluidic and Capillary Electrophoresis Applications