SIRT6 inhibits hypoxia-induced pulmonary arterial smooth muscle cells proliferation via HIF-1α/PDK4 signaling
Mingxing Li, Miaofa Ying, Shenglong Gu, Zheng Zhou, Rui Zhao
Topics & Concepts
Hypoxia (environmental)Cell biologyApoptosisSignal transductionCell growthSIRT6Gene knockdownPDK4ChemistryBiologyCancer researchNAD+ kinaseDownregulation and upregulationBiochemistrySirtuinEnzymeGeneOxygenOrganic chemistryPulmonary Hypertension Research and TreatmentsCardiovascular Function and Risk FactorsLiver Disease and Transplantation