KDM1A inhibition augments the efficacy of rapamycin for the treatment of endometrial cancer
Prabhakar Pitta Venkata, Yihong Chen, Salvador Alejo, Yi He, Bridgitte E. Palacios, Ilanna Loeffel, Junhao Liu, Uday P. Pratap, Gabrielle Gray, Sureshkumar Mulampurath Achuthan Pillai, Yi Zou, Zhao Lai, Takayoshi Suzuki, Suryavathi Viswanadhapalli, Srinath Palakurthi, Rajeshwar R. Tekmal, Ratna K. Vadlamudi, Edward R. Kost, Gangadhara R. Sareddy
Topics & Concepts
PI3K/AKT/mTOR pathwayTemsirolimusCancer researchProtein kinase BmTORC2BiologyChromatin immunoprecipitationMechanistic target of rapamycinSignal transductionCell biologymTORC1Gene expressionPromoterGeneBiochemistryDiscovery and development of mTOR inhibitorsEpigenetics and DNA MethylationHistone Deacetylase Inhibitors ResearchCancer Genomics and Diagnostics