Design, synthesis, and biological evaluation of novel 7-substituted 10,11-methylenedioxy-camptothecin derivatives against drug-resistant small-cell lung cancer in vitro and in vivo
Guorui Zhang, Ruijuan Yin, Xiufei Dai, Guanzhao Wu, Xin Qi, Rilei Yu, Jing Li, Tao Jiang
Topics & Concepts
CamptothecinTopotecanIrinotecanIn vivoChemistryPharmacologyLung cancerApoptosisXIAPCell growthIn vitroCancer researchCancerCaspaseBiologyProgrammed cell deathMedicineBiochemistryChemotherapyInternal medicineColorectal cancerBiotechnologyCancer therapeutics and mechanismsLung Cancer Research StudiesNeuroendocrine Tumor Research Advances