Antimicrobial Activity of Tannic Acid <i>In Vitro</i> and Its Protective Effect on Mice against Clostridioides difficile
Weigang Wang, Jing Cao, Jing Yang, Xiao-ran Niu, Xiaoxuan Liu, Yu Zhai, Cuixin Qiang, Yanan Niu, Zhirong Li, Ning Dong, Baojiang Wen, Zirou Ouyang, Yulian Zhang, Jiayiren Li, Min Zhao, Jianhong Zhao
Abstract
Clostridioides difficile is one of the major pathogens to cause antibiotic-associated diarrhea. Although antibiotic treatment is still the most commonly used and effective treatment for CDI, the destruction of indigenous intestinal microbiota by antibiotics is the main reason for the high CDI recurrence rate of about 20%, which is increasing every year.
Topics & Concepts
ClostridioidesAntibioticsTannic acidAntimicrobialDiarrheaMicrobiologyMedicineBiologyInternal medicineBotanyClostridium difficile and Clostridium perfringens researchGut microbiota and healthGastrointestinal motility and disorders