Simultaneous LC-MS/MS bioanalysis of alkaloids, terpenoids, and flavonoids in rat plasma through salting-out-assisted liquid-liquid extraction after oral administration of extract from Tetradium ruticarpum and Glycyrrhiza uralensis: a sample preparation strategy to broaden analyte coverage of herbal medicines
Manlin Li, Hanxue Wang, Xiaohan Huan, Ning Cao, Huida Guan, Hongmei Zhang, Xuemei Cheng, Changhong Wang
Topics & Concepts
ChromatographyChemistryGlycyrrhiza uralensisLiquiritinRutaecarpineBioanalysisAnalyteExtraction (chemistry)LiquiritigeninAmmonium acetateLiquid–liquid extractionEthyl acetateSample preparationRepeatabilityHigh-performance liquid chromatographyPathologyMedicineAlternative medicinePharmacological Effects of Natural CompoundsPlant-based Medicinal ResearchSynthesis and bioactivity of alkaloids