Copper(<scp>i</scp>) halide and palladium(<scp>ii</scp>) chloride complexes of 4-thioxo[1,3,5]oxadiazocines: synthesis, structure and antibacterial activity
Andrey Kuzovlev, Daria A. Volkova, Irina V. Parfenova, И. В. Кулаков, Alena O. Shkirdova, Ilya A. Zamilatskov, Владимир В. Чернышев, Victor B. Rybakov, Vladimir S. Tyurin, Nikolay Fefilov, Alexey S. Vasilchenko
Abstract
The first copper(<sc>i</sc>) and palladium(<sc>ii</sc>) complexes containing monastrol analogs, 4-thioxo[1,3,5]oxadiazocine derivatives, have been synthesized. The complexes demonstrated significant antibacterial activity in contrast to free heterocyclic thiones.
Topics & Concepts
ChemistryHalidePalladiumAntibacterial activityCopperChlorideCombinatorial chemistryOrganic chemistryBacteriaCatalysisBiologyGeneticsMetal complexes synthesis and propertiesSynthesis and Biological EvaluationCatalytic C–H Functionalization Methods