Exploring of novel 4-hydroxy-2H-benzo[e][1,2]thiazine-3-carbohydrazide 1,1-dioxide derivative as a dual inhibitor of α-glucosidase and α-amylase: Molecular docking, biochemical, enzyme kinetic and in-vivo mouse model study
Saman Taj, Matloob Ahmad, Usman Ali Ashfaq
Topics & Concepts
BenzothiazineChemistryCarbohydrazideEnzymeIC50AmylasePharmacologyBiochemistryMedicinal chemistryMedicineIn vitroNatural Antidiabetic Agents StudiesSynthesis and biological activityEnzyme function and inhibition