TH5487, a small molecule inhibitor of OGG1, attenuates pulmonary fibrosis by NEDD4L-mediated OGG1 degradation
Huayu Ling, Chuge Song, Yaowei Fang, Yu Yin, Zijun Wu, Yahong Wang, Zhiliang Xu, Shenglan Gao, Ao Li, Gang Liu
Topics & Concepts
BleomycinPulmonary fibrosisUbiquitin ligaseCancer researchFibrosisUbiquitinIdiopathic pulmonary fibrosisLungEpithelial–mesenchymal transitionChemistryPathologyBiologyMedicineDownregulation and upregulationBiochemistryChemotherapyInternal medicineGeneInterstitial Lung Diseases and Idiopathic Pulmonary FibrosisPneumonia and Respiratory InfectionsChronic Obstructive Pulmonary Disease (COPD) Research