Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm
P. Naresh Kumar, Steven Henikoff, Pauline C. Ng
Topics & Concepts
GeneticsScale-invariant feature transformBiologySequence alignmentCoding regionPhenotypeMutationSingle-nucleotide polymorphismComputational biologyGenePeptide sequenceComputer scienceGenotypeArtificial intelligenceFeature extractionRNA and protein synthesis mechanismsGenomics and Phylogenetic StudiesMachine Learning in Bioinformatics