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Multicenter Evaluation of the Cepheid Xpert Xpress SARS-CoV-2 Assay for the Detection of SARS-CoV-2 in Oropharyngeal Swab Specimens

Hongyan Hou, Jun Chen, Yueqin Wang, Yanjun Lu, Yaowu Zhu, Bo Zhang, Feng Wang, Lie Mao, Yi‐Wei Tang, Bicheng Hu, Yi Ren, Ziyong Sun

2020Journal of Clinical Microbiology23 citationsDOIOpen Access PDF

Abstract

The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a global health concern that has spread worldwide since December 2019 (1–4). For optimal detection of SARS-CoV-2, the collection and testing of either upper or lower respiratory samples are recommended (5–7). In China, oropharyngeal swab (OPS) specimens have been more widely used than nasopharyngeal swab (NPS) specimens as upper respiratory tract specimens for detection of SARS-CoV-2 during the early stages of COVID-19 outbreak (6).

Topics & Concepts

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)OutbreakVirology2019-20 coronavirus outbreakCoronavirusBetacoronavirusMedicineRespiratory tractRespiratory systemInternal medicineInfectious disease (medical specialty)DiseaseSARS-CoV-2 detection and testingRespiratory viral infections researchSARS-CoV-2 and COVID-19 Research