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Nanotechnology in medicine: a double-edged sword for health outcomes

Amanda Fortune, Aliunui Aimé, David J. Raymond, Sunil Kumar

2025Health Nanotechnology40 citationsDOIOpen Access PDF

Abstract

Nanotechnology has transformed contemporary medicine, providing exceptional developments in diagnostics, therapeutics, and individualized treatment approaches. Its applications range from targeted drug delivery to improved imaging and regenerative medicine. Nevertheless, these advances pose potential risks, requiring a judicious assessment of benefits and challenges. The incorporation of nanotechnology in medicine has greatly enhanced diagnostic accuracy, drug bioavailability, and disease-specific treatment options, especially in oncology and regenerative medicine. Nanoparticles facilitate targeted delivery with reduced systemic toxicity and increased therapeutic efficiency. Yet the same nanoscale characteristics that make this possible also lead to issues regarding biocompatibility, long-term toxicity, and immune system activation. Research shows that nanoparticles have the potential to accumulate in essential organs, cause oxidative stress, and be environmentally toxic because of their persistence in biological systems. In addition, regulatory discrepancies, expensive production, and public distrust hamper the widespread clinical use of nanomedicine. Although nanotechnology holds revolutionary medical potential, its ethical and safe application must be balanced. Regulated norms, strict risk analysis, and nanoparticle sustainable design are needed to minimize possible damages. Through interdisciplinary collaboration and the creation of global safety frameworks, nanotechnology can be leveraged to ensure maximum health gains with minimal unintended harm.

Topics & Concepts

SWORDNanotechnologyMedicineMaterials scienceEngineeringMechanical engineeringNanoparticles: synthesis and applicationsNanoparticle-Based Drug DeliveryGraphene and Nanomaterials Applications
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