Synthesis of 4-alkylaminoimidazo[1,2-a]pyridines linked to carbamate moiety as potent α-glucosidase inhibitors
Mina Saeedi, Maryam Raeisi-Nafchi, Sepideh Sobhani, Seyedeh Sara Mirfazli, Mahsa Zardkanlou, Somayeh Mojtabavi, Mohammad Ali Faramarzi, Tahmineh Akbarzadeh
Topics & Concepts
MoietyChemistryAcarboseCarbamateActive siteStereochemistryHydrogen bondDocking (animal)Lead compoundIC50Active compoundCombinatorial chemistryEnzymeIn vitroOrganic chemistryMoleculeBiochemistryMedicineNursingSynthesis and biological activityNatural Antidiabetic Agents StudiesSynthesis and Characterization of Heterocyclic Compounds