Exosomes in Renal Cell Cancer: Diagnostic and Therapeutic Nanovehicles
Stergios Boussios, Saak V. Ovsepian
Abstract
Early diagnosis is crucial for enhancing the survival rate of renal cell cancer patients, and exosomes present potential advantages in this area. Their small size, high mobility, and lipid bilayer structure enable exosomes to cross biological membranes easily, protecting the bioactive cargo within from degradation. Exosomes significantly influence the invasion and metastasis of RCC, and they also contribute to tumor drug resistance and immune evasion.
Topics & Concepts
MicrovesiclesImmune systemCancer researchMetastasisCancerCancer cellMedicineCellKidney cancerChemistryImmunologymicroRNAInternal medicineBiochemistryGeneExtracellular vesicles in diseaseFerroptosis and cancer prognosisNanoplatforms for cancer theranostics