An automated micro solid phase extraction gas chromatography–mass spectrometry (μSPE-GC–MS) detection method for geosmin and 2-methylisoborneol in drinking water
Robert Bristow, Adam Haworth‐Duff, Iain S. Young, P. Myers, M. R. Hampson, Jonathan Williams, Simon Maher
Abstract
Abstract Geosmin and 2-methylisoborneol (2-MIB) are amongst the most common earthy and musty taste and odour (T&O) compounds found in drinking water. With low odour threshold detection limits below 10 ng L −1 , and the complexity of raw water matrices, these two compounds provide a significant challenge for water companies globally. In this research, for the first time, a novel and fully automated micro-solid phase-extraction (μSPE) method coupled with gas chromatography (GC)–mass spectrometry (MS) has been developed for the detection of geosmin and 2-MIB for drinking water analysis. The new automated method described herein is environmentally friendly requiring low raw water sample volumes, of 25 mL, and only 50 μL of elution solvent. Our μSPE-GC–MS method exhibits excellent linearity for both compounds (R 2 > 0.999) and low limits of detection of 2.0 ng L −1 and 4.3 ng L −1 for geosmin and 2-MIB, respectively. The method showed excellent recovery rates (95.1–100.1%) and good precision (RSD < 7%) in raw sample matrices. Our approach is fully automated onto a robotic workstation which can be readily integrated into a laboratory workflow for routine water analysis. Furthermore, the method has excellent potential to be incorporated within a portable system for onsite analysis.