As3MT-mediated SAM consumption, which inhibits the methylation of histones and LINE1, is involved in arsenic-induced male reproductive damage
Lu Wu, Han Li, Fuping Ye, Yongyue Wei, Wenqi Li, Yue Xu, Haibo Xia, Jingshu Zhang, Lianxian Guo, Guiwei Zhang, Feng Chen, Qizhan Liu
Topics & Concepts
SpermatogenesisBiologyDNA damageMethyltransferaseReproductive toxicityAndrologyApoptosisGerm cellMethylationGene knockdownHistoneDNA methylationInternal medicineEndocrinologyToxicityGeneticsDNAGene expressionMedicineGeneSperm and Testicular FunctionEpigenetics and DNA MethylationRenal and related cancers