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Design, synthesis and biological evaluation of 7–(5–((substituted – amino)-methyl)-thiophen–2–yl)-spiro-[chroman–2,4′–piperidin]–4–one hydrochloride analogues as anticancer agents

Surendar Chitti, Sravani Pulya, Adinarayana Nandikolla, Tarun Patel, Banoth Karan Kumar, Sankaranarayanan Murugesan, Balaram Ghosh, Kondapalli Venkata Gowri Chandra Sekhar

2021Bioorganic Chemistry20 citationsDOI

Topics & Concepts

ChemistryADMEApoptosisCytotoxicityHydrochlorideCell cultureIn silicoStereochemistryCell growthGuanidineCarbon-13 NMRCell cyclePharmacologyBiochemistryIn vitroGeneticsGeneBiologyMedicineSynthesis of Organic CompoundsSynthesis and biological activitySynthesis and Characterization of Heterocyclic Compounds
Design, synthesis and biological evaluation of 7–(5–((substituted – amino)-methyl)-thiophen–2–yl)-spiro-[chroman–2,4′–piperidin]–4–one hydrochloride analogues as anticancer agents | Litcius