Synthesis and characterization of Se doped Fe3O4 nanoparticles for catalytic and biological properties
Mohammad Reza Ahghari, Zeinab Amiri-Khamakani, Ali Maleki
Abstract
Abstract In this study, Se-doped Fe 3 O 4 with antibacterial properties was synthesized using by a coprecipitation method. The chemistry and morphology of the Se doped Fe 3 O 4 nanocomposite were characterized by energy-dispersive X-ray spectroscopy, field-emission scanning electron microscopy, X-ray diffraction, vibrating sample magnetometry, and Brunauer–Emmett–Teller spectroscopy. The antibacterial activity of the Fe 3 O 4 /Se nanocomposite was examined against G + (Gram-positive) and G − (Gram-negative) bacteria, in the order Staphylococcus aureus , Staphylococcus saprophyticus , Pseudomonas aeruginosa , Klebsiella pneumonia , and Escherichia coli , which are the most harmful and dangerous bacteria. Fe 3 O 4 /Se, as a heterogeneous catalyst, was successfully applied to the synthesis of pyrazolopyridine and its derivatives via a one-pot four-component reaction of ethyl acetoacetate, hydrazine hydrate, ammonium acetate, and various aromatic aldehydes. Fe 3 O 4 /Se was easily separated from the bacteria-containing solution using a magnet. Its admissible magnetic properties, crystalline structure, antibacterial activity, mild reaction conditions, and green synthesis are specific features that have led to the recommendation of the use of Fe 3 O 4 /Se in the water treatment field and medical applications. Direct Se doping of Fe 3 O 4 was successfully realized without additional complicated procedures.