Recent advances in the three-component synthesis of difluorinated compounds
Zhan‐Yong Wang, Ziyan Zhang, Weiyi Chen, Liu Yang, Aili Sun, Ran Xia
Abstract
Three-component reactions enable easy difluorinated-compound synthesis. Advances from 2014–2024 have been categorized as (a) radical, (b) difluorocarbene, (c) nucleophilic or electrophilic fluorine routes.
Topics & Concepts
Component (thermodynamics)ChemistryComputer sciencePhysicsThermodynamicsFluorine in Organic ChemistrySynthesis and Reactions of Organic CompoundsSynthesis and Biological Evaluation