Neural-enhancing PRP/Alg/GelMA triple-network hydrogel for neurogenesis and angiogenesis after spinal cord injury via PI3K/AKT/mTOR signaling pathway
Zhihe Yun, Jiuping Wu, Xinzhi Sun, Yu Tao, Xue Wu, Anyuan Dai, Tianyang Yuan, Xuhao Yang, Inbo Han, Yanting Liu, Wenlong Song, Qinyi Liu
Abstract
The neural regeneration-enhanced triple-network hydrogel we developed has excellent dual biological functions of neural regeneration and angiogenesis, and it is a straightforward, viable, and promising therapeutic strategy for SCI regeneration.
Topics & Concepts
NeurogenesisPI3K/AKT/mTOR pathwayAngiogenesisProtein kinase BSpinal cord injuryMedicineSpinal cordNeuroscienceSignal transductionCancer researchBiologyCell biologySpinal Cord Injury ResearchNerve injury and regeneration