Stereoselective synthesis of functionalized azepines <i>via</i> gold and palladium relay catalysis
Wu‐Lin Yang, Jiahuan Shen, Zenghui Zhao, Zhongao Wang, Wei‐Ping Deng
Abstract
We developed a cycloisomerization/asymmetric [4 + 3] cycloaddition cascade reaction via gold/palladium relay catalysis, furnishing enantioenriched furan-fused azepines efficiently.
Topics & Concepts
CycloisomerizationChemistryFuranPalladiumCycloadditionCatalysisCascadeStereoselectivityCombinatorial chemistryRelayReaction conditionsOrganic chemistryQuantum mechanicsPhysicsChromatographyPower (physics)Catalytic Alkyne ReactionsCatalytic C–H Functionalization MethodsCyclopropane Reaction Mechanisms