Interspecies effectors of a transgenerational memory of bacterial infection in Caenorhabditis elegans
Marcela Legüe, Mauricio Caneo, Blanca Aguila, Bernardo Pollak, Andrea Calixto
Abstract
The HMT SET-25/EHMT2 is necessary for memory maintenance in the transgenerational lineage. Our work is a starting point to understanding microbiome-induced inheritance of acquired traits, and the transgenerational influence of microbes in health and disease.
Topics & Concepts
Caenorhabditis elegansTransgenerational epigeneticsEffectorBiologyCaenorhabditisComputational biologyGeneticsCell biologyGeneEpigeneticsGenetics, Aging, and Longevity in Model OrganismsEvolution and Genetic DynamicsCRISPR and Genetic Engineering