Sesamol as a potential candidate for the treatment of hepatic fibrosis, based on its regulation of FXR/LXR axis-mediated inhibition of autophagy through crosstalk between hepatic cells and macrophage
YuChen Jiang, Li‐Shuang Hou, Jiayi Dou, Meiyan Xuan, Zhenyu Cui, Li‐Hua Lian, Ji‐Xing Nan, Yan‐Ling Wu
Topics & Concepts
AutophagyHepatic fibrosisChemistryHepatic stellate cellProinflammatory cytokineFibrosisInternal medicineEndocrinologyHepatoprotectionLiver X receptorPharmacologyBiologyInflammationMedicineTranscription factorApoptosisBiochemistryGlutathioneNuclear receptorGeneEnzymeSesame and Sesamin ResearchLiver physiology and pathologyLiver Disease Diagnosis and Treatment