The Association of Salivary Serotonin With Mood and Cardio-Autonomic Function: A Preliminary Report
Michał Seweryn Karbownik, Steven D. Hicks
Abstract
Background: Serotonin plays an important role in mood regulation and depression. However, it is not clear whether the levels of serotonin in saliva are related to current mood. Aim: To test the association of salivary serotonin concentrations with mood, as well as cardiovascular and autonomic parameters. Materials and Methods: Saliva samples were obtained from collegiate runners and output parameters were examined before and after physical activity. Results: = 0.037, analysis adjusted for potential confounders), but insignificantly with measured cardiovascular and autonomic parameters. Conclusions: Salivary serotonin may reflect current mood. The results are preliminary and require further evaluation.