Burden of aneurysmal subarachnoid haemorrhage deaths in middle-aged people is relatively high
Ilari Rautalin, Jaakko Kaprio, Miikka Korja
Abstract
The number of deaths resulting from aneurysmal subarachnoid haemorrhage (aSAH) is commonly considered negligible in comparison with other causes of death. In fact, it has been estimated that subarachnoid haemorrhage accounts for only 4% of stroke deaths.1 However, addressing the aSAH death toll is challenging since many aSAH deaths happen outside of hospitals and are commonly classified as cardiac deaths when autopsies are not done.2 3 Middle-aged people are affected most frequently by aSAH. Since cancer-, traffic-, alcohol- and cardiovascular-related deaths are decreasing in middle-aged people in high-income countries,4 we hypothesise that the proportion of aSAH deaths may be increasing in this age group. Therefore, we aimed to determine the proportion of aSAH deaths relative to other causes of death in middle-aged people. ### Ethical considerations Statistics Finland and the National Institute of Health and Welfare approved the data extractions and analysis from the nationwide Cause of Death (CDR) and Hospital Discharge Registers (HDR). According to Finnish legislation, no separate informed consent was required, as we did not access personally identifiable information. ### Study period Since 1936, all deaths in Finland have been archived to the nationwide CDR governed by Statistics Finland. The causes of death have been classified using the 10th version of the International Statistical Classification of Diseases and Related Health Problems (ICD-10) coding from 1996 onwards. To avoid possible misclassification immediately after the transition to ICD-10, we included death diagnoses between 1998 and 2017. ### Causes of death We extracted aSAH deaths registered to the CDR with the four-character ICD-10 classification codes (I60.0–I60.6). We used the nationwide …