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A fluorescent probe strategy for the detection and discrimination of hydrogen peroxide and peroxynitrite in cells

Hannah R. Bolland, Ester M. Hammond, Adam C. Sedgwick

2022Chemical Communications30 citationsDOIOpen Access PDF

Abstract

at 460 nm (blue channel) in solution and in cells. This work also highlights the choice of fluorophore before boronate functionalization can dictate the observed selectivity between these two species.

Topics & Concepts

PeroxynitriteHydrogen peroxideFluorescenceChemistryPhotochemistryCombinatorial chemistryNanotechnologyBiophysicsBiochemistryMaterials scienceBiologySuperoxideEnzymePhysicsOpticsMolecular Sensors and Ion DetectionNitric Oxide and Endothelin EffectsSulfur Compounds in Biology
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