Dysregulated Amino Acid Sensing Drives Colorectal Cancer Growth and Metabolic Reprogramming Leading to Chemoresistance
Sumeet Solanki, Katherine Sanchez, Varun Ponnusamy, Vasudha Kota, Hannah N. Bell, Chun‐Seok Cho, Allison H. Kowalsky, Michael Green, Jun Hee Lee, Yatrik M. Shah
Topics & Concepts
mTORC1Amino acidCancer researchNutrient sensingBiologyColorectal cancerSignal transductionCarcinogenesisCancerCell biologyBiochemistryPI3K/AKT/mTOR pathwayGeneticsCancer Research and TreatmentsPI3K/AKT/mTOR signaling in cancerAmino Acid Enzymes and Metabolism