Exhaled Anesthetic Xenon Regeneration by Gas Separation Using a Metal–Organic Framework with Sorbent‐Sorbate Induced‐Fit
Li Zhao, Xiaowan Peng, Chenghua Deng, Jia‐Han Li, Huiyuan Pan, Jin‐Sheng Zou, Bei Liu, Chun Deng, Peng Xiao, Chang‐Yu Sun, Yun‐Lei Peng, Guangjin Chen, Guangjin Chen, Michael J. Zaworotko
Abstract
Abstract Noble gas xenon (Xe) is an excellent anesthetic gas, but its rarity, high cost and constrained production prohibits wide use in medicine. Here, we have developed a closed‐circuit anesthetic Xe recovery and reusage process with highly effective CO 2 ‐specific adsorbent CUPMOF‐5 that is promising to solve the anesthetic Xe supply problem. CUPMOF‐5 possesses spacious cage cavities interconnected in four directions by confinement throat apertures of ~3.4 Å, which makes it an ideal molecular sieving of CO 2 from Xe, O 2 , N 2 with the benchmark selectivity and high uptake capacity of CO 2 . In situ single‐crystal X‐ray diffraction (SCXRD) and computational simulation solidly revealed the vital sieving role of the confined throat and the sorbent‐sorbate induced‐fit strengthening binding interaction to CO 2 . CUPMOF‐5 can remove 5 % CO 2 even from actual moist exhaled anesthetic gases, and achieves the highest Xe recovery rate (99.8 %) so far, as verified by breakthrough experiments. This endows CUPMOF‐5 great potential for the on‐line CO 2 removal and Xe recovery from anesthetic closed‐circuits.