A cubic Cu<sub>2</sub>O@Ag bioprobe for label-free SERS classification of hepatic fibrosis and hepatocellular carcinoma
Yujiao Xie, Xue Li, Lei Xu, Chenguang Zhang, Yong Ren, Xiaofeng Shi, Liyun Fu, Jing Wang, Xiawei Xu, Yue Liu, Yue Hu, Zhouxu Zhang, J.Y. Zhang, Ting Yao, Wenzhi Ren, Tianxiang Chen, Xiaoyu Qian, Xiaotian Wang, Jie Lin, Aiguo Wu
Abstract
In this study, a cubic Cu 2 O@Ag core–shell substrate for label-free SERS was constructed and machine-learning-assisted linear discriminant analysis was used for identification of hepatic fibrosis and hepatocellular carcinoma.
Topics & Concepts
Hepatocellular carcinomaShell (structure)Materials scienceMedicineInternal medicineComposite materialAdvanced Nanomaterials in CatalysisGold and Silver Nanoparticles Synthesis and ApplicationsNanocluster Synthesis and Applications