Litcius/Paper detail

COVID‐19 associated pulmonary aspergillosis

Philipp Koehler, Oliver A. Cornely, Bernd W. Böttiger, Fabian Dusse, Dennis A. Eichenauer, Frieder Fuchs, Michael Hallek, Norma Jung, Florian Klein, Thorsten Persigehl, Jan Rybniker, Matthias Kochanek, Boris Böll, Alexander Shimabukuro‐Vornhagen

2020Mycoses551 citationsDOIOpen Access PDF

Abstract

OBJECTIVES: Patients with acute respiratory distress syndrome (ARDS) due to viral infection are at risk for secondary complications like invasive aspergillosis. Our study evaluates coronavirus disease 19 (COVID-19) associated invasive aspergillosis at a single centre in Cologne, Germany. METHODS: A retrospective chart review of all patients with COVID-19 associated ARDS admitted to the medical or surgical intensive care unit at the University Hospital of Cologne, Cologne, Germany. RESULTS: COVID-19 associated invasive pulmonary aspergillosis was found in five of 19 consecutive critically ill patients with moderate to severe ARDS. CONCLUSION: Clinicians caring for patients with ARDS due to COVID-19 should consider invasive pulmonary aspergillosis and subject respiratory samples to comprehensive analysis to detect co-infection.

Topics & Concepts

Pulmonary aspergillosisCoronavirus disease 2019 (COVID-19)AspergillosisMedicine2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)VirologyPathologyImmunologyInfectious disease (medical specialty)OutbreakDiseaseAntifungal resistance and susceptibilityOtolaryngology and Infectious DiseasesInfective Endocarditis Diagnosis and Management