Distinctive populations of CD4+T cells associated with vaccine efficacy
Therese Woodring, Colin N. Dewey, Lucas dos Santos Dias, Xin He, Hannah E. Dobson, Marcel Wüthrich, Bruce S. Klein
Abstract
expressing populations. Our findings highlight key features of transcriptionally diverse and distinctive antigen-specific T cells associated with protective vaccine-induced immunity.
Topics & Concepts
BiologyImmunityTranscriptomeInterferonImmunologyT-cell receptorPopulationGeneAntigenT cellVirologyGeneticsImmune systemGene expressionMedicineEnvironmental healthImmune Cell Function and InteractionT-cell and B-cell ImmunologyCAR-T cell therapy research