Recent progress in nickel-catalyzed carboboration of alkenes
Yang Ye, Ying‐Chih Lin, Nian‐Dong Mao, Huimin Yang, Xiang‐Yang Ye, Tian Xie
Abstract
. Despite this progress, a number of challenging issues remaining in the field include broadening the types of carboboration reactions, especially the asymmetric ones, diversifying electrophile types (which is limited to halogens for now) and gaining profound insight into the reaction mechanisms. This review summarizes the recent progress in this emerging field from the literature published since 2018. It will provide the scientific community with convenience to access collective information and to accelerate their further research in order to broaden the scope of methodology and application in drug discovery programs.
Topics & Concepts
NickelCatalysisComputer scienceChemistryOrganic chemistryOrganoboron and organosilicon chemistryCatalytic Cross-Coupling ReactionsChemical Synthesis and Analysis