Ultra-performance liquid chromatography-tandem mass spectrometry for simultaneous determination of 12 anti-tumor drugs in human plasma and its application in therapeutic drug monitoring
Guofei Li, Mingming Zhao, Limei Zhao
Topics & Concepts
ChemistryChromatographyTherapeutic drug monitoringPharmacokineticsCapecitabineLiquid chromatography–mass spectrometryProtein precipitationSolid phase extractionHigh-performance liquid chromatographyPharmacologyMass spectrometryCancerInternal medicineMedicineColorectal cancerCancer Treatment and PharmacologyCancer therapeutics and mechanismsChemotherapy-induced organ toxicity mitigation