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LRRC8A:C/E Heteromeric Channels Are Ubiquitous Transporters of cGAMP

Lauren J. Lahey, Rachel E. Mardjuki, Xianlan Wen, Gaelen T. Hess, Christopher Ritchie, Jacqueline A. Carozza, Volker Böhnert, Merritt Maduke, Michael C. Bassik, Lingyin Li

2020Molecular Cell186 citationsDOIOpen Access PDF

Topics & Concepts

BiologyCell biologyTransporterExtracellularIon channelInnate immune systemBiochemistryGeneReceptorinterferon and immune responsesMosquito-borne diseases and controlInvertebrate Immune Response Mechanisms
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