Light-Driven Carbon–Carbon Coupling of α-sp <sup>3</sup> –CH of Aliphatic Alcohols with sp <sup>2</sup> –CH Bond of 1,4-Naphthoquinones
Raushan Kumar Jha, Aditya Upadhyay, Kanika, Saket Jain, K A Neena, Sangit Kumar
Abstract
Here, an α-selective C sp3 –H bond functionalization of primary aliphatic alcohols with 1,4-naphthoquinones yielded C sp 2 –C sp 2 coupled products driven by blue-LED light under catalyst, metal, base, and reagent-free conditions. In this transformation, cleavage of three C–H bonds (two sp 3 –C-H, one sp 2 –C–H, and one O–H) and four new bonds formed, leading to fluorescent 2-acylated-1,4-naphthohydroquinones.
Topics & Concepts
ChemistryCarbon fibersCarbon–carbon bondCoupling (piping)Carbon chainPhotochemistryOrganic chemistryMedicinal chemistryCatalysisComposite materialComposite numberEngineeringMaterials scienceMechanical engineeringCatalytic C–H Functionalization MethodsRadical Photochemical ReactionsSulfur-Based Synthesis Techniques