“PROTAC” modified dihydroquinolizinones (DHQs) that cause degradation of PAPD-5 and inhibition of hepatitis A virus and hepatitis B virus, in vitro
You Li, Nicky Hwang, Andrew Snedeker, Stanley M. Lemon, Daisy Noe, Liren Sun, Jason A. Clement, Tianlun Zhou, Liudi Tang, Timothy M. Block, Yanming Du
Topics & Concepts
In vitroHepatitis B virusChemistryHBsAgProteolysisVirusVirologyIn vivoIC50Molecular biologyBiochemistryBiologyEnzymeBiotechnologyProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysMultiple Myeloma Research and Treatments