Hyperexcitable Phenotypes in Induced Pluripotent Stem Cell–Derived Neurons From Patients With 15q11-q13 Duplication Syndrome, a Genetic Form of Autism
James J. Fink, Jeremy D. Schreiner, Judy E. Bloom, Jadin James, Dylan Baker, Tiwanna M. Robinson, Richard Lieberman, Leslie M. Loew, Stormy J. Chamberlain, Eric S. Levine
Topics & Concepts
NeuroscienceInduced pluripotent stem cellBiologyMECP2HypotoniaInhibitory postsynaptic potentialExcitatory postsynaptic potentialAutism spectrum disorderPhenotypeAngelman syndromeAutismPsychologyEmbryonic stem cellGeneticsGenePsychiatryGenomic variations and chromosomal abnormalitiesAutism Spectrum Disorder ResearchGenetic Syndromes and Imprinting